Which statement regarding drug-induced gingival enlargement is correct?

The statement that discontinuing the drug will lead to the spontaneous disappearance of gingival enlargement is accurate. Drug-induced gingival enlargement, often associated with medications such as phenytoin, cyclosporine, and calcium channel blockers, can be significantly reduced or resolved following the cessation of the offending medication. It is important to note that while oral hygiene plays a critical role in managing and minimizing gingival inflammation, simply improving oral hygiene does not guarantee the resolution of the enlargement if the medication causing it is still being taken.

Conversely, the chance of recurrence after surgical removal is actually notable. If the causative agent remains in use, the tissue may grow back despite surgical intervention. Also, while good oral hygiene can help manage inflammation and reduce the risk of further enlargement, it does not completely prevent drug-induced gingival overgrowth. Lastly, genetic factors indeed play a role in determining an individual’s susceptibility to these types of gingival changes, so stating that genetic predisposition is not a factor would not be correct. Thus, the choice to discontinue the drug is the most reliable method for resolution of the condition.